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1

HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease

Benoy, Veronick, Van Helleputte, Lawrence, Prior, Robert, d’Ydewalle, Constantin, Haeck, Wanda, Geens, Natasja, Scheveneels, Wendy, Schevenels, Begga, Cader, M. Zameel, Talbot, Kevin, Kozikowski, Alan

Journal:

Year:

2018

Language:

english

File:

PDF, 813 KB

english, 2018

2

Common transcriptional signatures of neuropathic pain

Pokhilko, Alexandra, Nash, Anthony, Cader, M. Zameel

Journal:

Year:

2020

File:

PDF, 1.24 MB

2020

3

A first stage genome-wide screen for regions shared identical-by-descent in hutterite families with multiple sclerosis

David Alexandre Dyment, M. Zameel Cader, Anita Datta, S. John Broxholme, Stacey S. Cherny, Cristen J. Willer, Sreeram Ramagopalan, Blanca M. Herrera, Sarah Orton, Michael Chao, A. Dessa Sadovnick, Mar

Journal:

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Year:

2008

Language:

english

File:

PDF, 94 KB

english, 2008

4

Rare variants in the CYP27B1 gene are associated with multiple sclerosis

Sreeram V. Ramagopalan, David A. Dyment, M. Zameel Cader, Katie M. Morrison, Giulio Disanto, Julia M. Morahan, Antonio J. Berlanga-Taylor, Adam Handel, Gabriele C. De Luca, A. Dessa Sadovnick, Pierre

Journal:

Annals of Neurology

Year:

2011

Language:

english

File:

PDF, 125 KB

english, 2011

5

Genomewide linkage scan reveals novel loci modifying age of onset of Huntington's disease in the Venezuelan HD kindreds

Javier Gayán, Denise Brocklebank, J. Michael Andresen, Gorka Alkorta-Aranburu, M. Zameel Cader, Simone A. Roberts, Stacey S. Cherny, Nancy S. Wexler, Lon R. Cardon, David E. Housman

Journal:

Genetic Epidemiology

Year:

2008

Language:

english

File:

PDF, 189 KB

english, 2008

6

New directions in migraine

Greg A Weir, M Zameel Cader

Journal:

Year:

2011

Language:

english

File:

PDF, 213 KB

english, 2011

7

A predominant role for the HLA class II region in the association of the MHC region with multiple sclerosis

Lincoln, Matthew R, Montpetit, Alexandre, Cader, M Zameel, Saarela, Janna, Dyment, David A, Tiislar, Milvi, Ferretti, Vincent, Tienari, Pentti J, Sadovnick, A Dessa, Peltonen, Leena

Journal:

Nature Genetics

Year:

2005

Language:

english

File:

PDF, 186 KB

english, 2005

8

A dominant-negative mutation in the TRESK potassium channel is linked to familial migraine with aura

Lafrenière, Ronald G, Cader, M Zameel, Poulin, Jean-François, Andres-Enguix, Isabelle, Simoneau, Maryse, Gupta, Namrata, Boisvert, Karine, Lafrenière, François, McLaughlan, Shannon, Dubé, Marie-Pierre

Journal:

Nature Medicine

Year:

2010

Language:

english

File:

PDF, 1.09 MB

english, 2010

9

Neuropilins lock secreted semaphorins onto plexins in a ternary signaling complex

Janssen, Bert J C, Malinauskas, Tomas, Weir, Greg A, Cader, M Zameel, Siebold, Christian, Jones, E Yvonne

Journal:

Nature Structural and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 1.65 MB

english, 2012

10

Morphological analysis of neuromuscular junction development and degeneration in rodent lumbrical muscles

Sleigh, James N., Burgess, Robert W., Gillingwater, Thomas H., Cader, M. Zameel

Journal:

Journal of Neuroscience Methods

Year:

2014

Language:

english

File:

PDF, 311 KB

english, 2014

11

The molecular pathogenesis of migraine: new developments and opportunities

Zameel Cader, M.

Journal:

Human Molecular Genetics

Year:

2013

Language:

english

File:

PDF, 376 KB

english, 2013

12

Cloxyquin (5-chloroquinolin-8-ol) is an activator of the two-pore domain potassium channel TRESK

Wright, Paul D., Weir, Gregory, Cartland, Jamie, Tickle, David, Kettleborough, Catherine, Cader, M. Zameel, Jerman, Jeff

Journal:

Biochemical and Biophysical Research Communications

Year:

2013

Language:

english

File:

PDF, 1.06 MB

english, 2013

13

Functional Analysis of Mutations in the TRESK K2P Potassium Channel Associated with ‘migraine with Aura’

Andres-Enguix, Isabelle, Shang, Lijun, Stansfeld, Phillip, Sansom, Mark S.P., Cader, M. Zameel, Tucker, Stephen J.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 52 KB

english, 2011

14

Neuropilins Lock Secreted Semaphorins onto Plexins in a Ternary Signalling Complex

Malinauskas, Tomas, Janssen, Bert J.C., Weir, Greg A., Cader, M. Zameel, Siebold, Christian, Jones, E. Yvonne

Journal:

Biophysical Journal

Year:

2013

Language:

english

File:

PDF, 37 KB

english, 2013

15

Dominant, toxic gain-of-function mutations in gars lead to non-cell autonomous neuropathology

Grice, Stuart J., Sleigh, James N., Motley, William W., Liu, Ji-Long, Burgess, Robert W., Talbot, Kevin, Cader, M. Zameel

Journal:

Human Molecular Genetics

Year:

2015

Language:

english

File:

PDF, 1.12 MB

english, 2015

16

StemBANCC: Governing Access to Material and Data in a Large Stem Cell Research Consortium

Morrison, Michael, Klein, Christine, Clemann, Nicole, Collier, David A., Hardy, John, Heiβerer, Barbara, Cader, M. Zameel, Graf, Martin, Kaye, Jane

Journal:

Stem Cell Reviews and Reports

Year:

2015

Language:

english

File:

PDF, 277 KB

english, 2015

17

Next generation sequencing for molecular diagnosis of neurological disorders using ataxias as a model

Nemeth, A. H., Kwasniewska, A. C., Lise, S., Parolin Schnekenberg, R., Becker, E. B. E., Bera, K. D., Shanks, M. E., Gregory, L., Buck, D., Zameel Cader, M., Talbot, K., de Silva, R., Fletcher, N., Ha

Journal:

Year:

2013

Language:

english

File:

PDF, 722 KB

english, 2013

18

Reprogramming psychiatry: stem cells and bipolar disorder

Harrison, Paul J, Cader, M Zameel, Geddes, John R

Journal:

Year:

2016

Language:

english

File:

PDF, 573 KB

english, 2016

19

The effect of colchicine on cyclic AMP accumulation in NG108–15 cells

CADER, M. ZAMEEL, KEEN, MARY

Journal:

Biochemical Society Transactions

Year:

1995

Language:

english

File:

PDF, 116 KB

english, 1995

20

Most brain disease-associated and eQTL haplotypes are not located within transcription factor DNase-seq footprints in brain

Handel, Adam E., Gallone, Giuseppe, Cader, M. Zameel, Ponting, Chris P.

Journal:

Human Molecular Genetics

Year:

2016

Language:

english

File:

PDF, 1.07 MB

english, 2016

21

Mitophagy and Alzheimer’s Disease: Cellular and Molecular Mechanisms

Kerr, Jesse S., Adriaanse, Bryan A., Greig, Nigel H., Mattson, Mark P., Cader, M. Zameel, Bohr, Vilhelm A., Fang, Evandro F.

Journal:

Trends in Neurosciences

Year:

2017

Language:

english

File:

PDF, 3.02 MB

english, 2017

22

Trk receptor signalling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations

Sleigh, J.N., Dawes, J., West, S.J., Wei, N., Spaulding, E.L., Gómez-Martín, A., Zhang, Q., Burgess, R.W., Zameel Cader, M., Talbot, K., Yang, X.-L., Bennett, D.L., Schiavo, G.

Journal:

Neuromuscular Disorders

Year:

2017

Language:

english

File:

PDF, 129 KB

english, 2017

23

Trk receptor signaling and sensory neuron fate are perturbed in human neuropathy caused by Gars mutations

Sleigh, James N., Dawes, John M., West, Steven J., Wei, Na, Spaulding, Emily L., Gómez-Martín, Adriana, Zhang, Qian, Burgess, Robert W., Cader, M. Zameel, Talbot, Kevin, Yang, Xiang-Lei, Bennett, Davi

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.96 MB

english, 2017

24

Engineered method for directional growth of muscle sheets on electrospun fibers

Soliman, Erfan, Bianchi, Fabio, Sleigh, James N, George, Julian H, Cader, M Zameel, Cui, Zhanfeng, Ye, Hua

Journal:

Journal of Biomedical Materials Research Part A

Year:

2017

Language:

english

File:

PDF, 2.62 MB

english, 2017

25

Neurovascular dysfunction in dementia – human cellular models and molecular mechanisms

Parkes, Isobel, Chintawar, Satyan, Cader, M. Zameel

Journal:

Clinical Science

Year:

2018

Language:

english

File:

PDF, 1016 KB

english, 2018

26

Aligned electrospun fibers for neural patterning

Soliman, Erfan, Bianchi, Fabio, Sleigh, James N., George, Julian H., Cader, M. Zameel, Cui, Zhanfeng, Ye, Hua

Journal:

Biotechnology Letters

Year:

2018

Language:

english

File:

PDF, 1.12 MB

english, 2018

27

Small vessels, dementia and chronic diseases – molecular mechanisms and pathophysiology

Horsburgh, Karen, Wardlaw, Joanna M., van Agtmael, Tom, Allan, Stuart M., Ashford, Mike L.J., Bath, Philip M., Brown, Rosalind, Berwick, Jason, Cader, M. Zameel, Carare, Roxana O., Davis, John B., Dun

Journal:

Clinical Science

Year:

2018

Language:

english

File:

PDF, 888 KB

english, 2018

28

EBNA2 Binds to Genomic Intervals Associated with Multiple Sclerosis and Overlaps with Vitamin D Receptor Occupancy

Ricigliano, Vito A. G., Handel, Adam E., Sandve, Geir K., Annibali, Viviana, Ristori, Giovanni, Mechelli, Rosella, Cader, M. Zameel, Salvetti, Marco, Makishima, Makoto

Journal:

Year:

2015

Language:

english

File:

PDF, 327 KB

english, 2015

29

Plexin-Semaphorin Signaling Modifies Neuromuscular Defects in a Drosophila Model of Peripheral Neuropathy

Grice, Stuart J., Sleigh, James N., Zameel Cader, M.

Journal:

Frontiers in Molecular Neuroscience

Year:

2018

Language:

english

File:

PDF, 3.04 MB

english, 2018

30

The Role of TRESK in Discrete Sensory Neuron Populations and Somatosensory Processing

Weir, Greg A., Pettingill, Philippa, Wu, Yukyee, Duggal, Galbha, Ilie, Andrei-Sorin, Akerman, Colin J., Cader, M. Zameel

Journal:

Frontiers in Molecular Neuroscience

Year:

2019

Language:

english

File:

PDF, 5.24 MB

english, 2019

31

Targeted next generation sequencing identifies a genetic spectrum of DNA variants in patients with hemiplegic migraine

Maksemous, Neven, Smith, Robert A, Sutherland, Heidi G, Maher, Bridget H, Ibrahim, Omar, Nicholson, Garth A, Carpenter, Elisabeth P, Lea, Rod A, Cader, M Zameel, Griffiths, Lyn R

Journal:

Cephalalgia Reports

Year:

2019

Language:

english

File:

PDF, 662 KB

english, 2019

32

Targeted next generation sequencing identifies a genetic spectrum of DNA variants in patients with hemiplegic migraine

Maksemous, Neven, Smith, Robert A, Sutherland, Heidi G, Maher, Bridget H, Ibrahim, Omar, Nicholson, Garth A, Carpenter, Elisabeth P, Lea, Rod A, Cader, M Zameel, Griffiths, Lyn R

Journal:

Cephalalgia Reports

Year:

2019

File:

PDF, 662 KB

2019

33

Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples

Curion, Fabiola, Handel, Adam E, Attar, Moustafa, Gallone, Giuseppe, Bowden, Rory, Cader, M. Zameel, Clark, Michael B

Journal:

Year:

2020

File:

PDF, 3.20 MB

2020

34

TRESK is a key regulator of nocturnal suprachiasmatic nucleus dynamics and light adaptive responses

Lalic, Tatjana, Steponenaite, Aiste, Wei, Liting, Vasudevan, Sridhar R., Mathie, Alistair, Peirson, Stuart N., Lall, Gurprit S., Cader, M. Zameel

Journal:

Nature Communications

Year:

2020

File:

PDF, 1.39 MB

2020

35

[Progress in Brain Research] Update on Emerging Treatments for Migraine Volume 255 || The genetics of migraine and the path to precision medicine

Cader, M. Zameel

Year:

2020

File:

PDF, 266 KB

2020